Accumulating evidence supports the role of defects in post-transcriptional gene regulation in the development of cancer. RNA and Cancer focuses on the recent advances in our understanding of post-transcriptional gene regulation, especially RNA processing and its role in cancer development and treatment. INDICE: Foreword.- Coupling between Transcription and Alternative Splicing.- Detection of Alternatively Spliced or Processed RNAs in Cancer using Oligonucleotide Microarray.- Cancer-associated Perturbations in Alternative Pre-messenger RNA Splicing.- Alternative Splicing of Tumor Suppressors and Oncogenes.-Imaging Alternative Splicing and Epithelial Plasticity in Tumor Cells and Tumors.- Alternative pre-mRNA splicing and regulation of cell death.- MIA melanoma?.- RNA localization/degradation.- RNA binding proteins and cancer.- Oligonucleotide cancer therapeutics.- Effects of anti-cancer drug on splicing.- Index.
- ISBN: 978-1-4419-0021-0
- Editorial: Springer
- Encuadernacion: Cartoné
- Páginas: 310
- Fecha Publicación: 28/08/2012
- Nº Volúmenes: 1
- Idioma: Inglés