Multifunctional Nanoparticles for Cancer Therapeutic Applications: Design and Challenges

Multifunctional Nanoparticles for Cancer Therapeutic Applications: Design and Challenges describes the use of multifunctional nanoparticles for cancer treatment, highlighting their toxicological evaluation and opportunities for prospective clinical therapeutic development. Besides significant research and clinical success, cancer nanomedicines currently face challenges towards clinical translation and this book aims to shed a light on complex issues. It discusses topics such as synthetic strategies and functionalization of nanoparticles; routes of administration; biological barriers and how to overcome them; nanoparticles for cancer treatment available in the market; active targeting approach; non-viral gene-based therapy with multifunctional nanoparticles; and the use of nanoparticles in immunotherapy. In addition, it discusses image guided cancer therapy; stem cell targeted therapy; and toxicity. It is a valuable resource for cancer researchers, oncologists, clinicians, and members of biomedical field who need to understand the potential of multifunctional nanoparticles in cancer drug delivery, diagnosis, and treatment. Presents an interdisciplinary approach on the application of nanoparticles in cancer therapy by bringing together experts from academia, clinical setting, and industryAddresses the main clinical challenges for the therapeutic use of nanoparticles for cancer treatment, including toxicity evaluation for specific cancer typesFocuses on intervening the biological barriers with combinational cancer therapies with the use of multifunctional nanoparticles INDICE: 1. Synthetic strategies of nanoparticles: scale up strategies and issues2. Functionalization of nanoparticles3. Characterization of nano particles intended for tumor therapy4. Routes of administration of nanoparticles5. Structures of multifunctional nanoparticle platforms6. Crossing the biological barriers: multifunctional nanoparticles7. Nanoparticles for cancer therapeutic application in the market/clinical phases8. Challenges with active targeting approach using Multifunctional nanoparticles9. Internal stimuli-responsive targeting system10. External stimuli-responsive nano system11. Bio inspired nanomaterials in cancer theragnostic: liposomes, lipids, protein and viral based multifunctional nanoparticles12. Biomimetic Magnetic Nanoparticles in cancer theragnostic13. Non-viral gene-based tumor therapy using multifunctional nanoparticles14. Cancer immunotherapy: mechanism, advantages, and role of nanoparticles15. Liposomes-Based Nanoparticles for Tumor Therapy and in vivo imaging16. Quantum Dots for Cancer diagnosis and Therapy17. Polymeric Nanoparticles for Cancer diagnosis and Therapy18. Stem cell targeted cancer therapy: role of nanoparticles19. Gold Nanoparticles for tumor Imaging and Therapy20. Image guided cancer therapy: a new approach using multifunctional nanoparticle21. Protein corona over nanoparticles: implications and strategies for cancer therapy22. Multifunctional nanoparticle induced toxicity: invitro, in vivo and its bioelimination

• ISBN: 978-0-443-21686-2
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 600
• Fecha Publicación: 01/01/2025
• Nº Volúmenes: 1
• Idioma: Inglés