Biopharmaceutics and Pharmacokinetics Considerations examines the history as well as the current state of the field within pharmaceutical sciences and concisely explains the history of biopharmaceutics and pharmacokinetics including key developments. It provides a biopharmaceutics and pharmacokinetics approach to addressing issues in formulation development and ethical considerations in handling animals. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biopharmaceutics and pharmacokinetics within drug discovery and drug development. Each chapter delves into a particular aspect of this fundamental field to cover the principles, methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to study the chemical and physical properties of drugs and the biological effects they produce as well as the movement of drugs within the body. This book provides a comprehensive examination suitable for researchers working in the pharmaceutical, cosmetics, biotechnology, and related industries as well as advanced students in these fields. Examines the most recent developments in biopharmaceutics and pharmacokinetics for pharmaceutical sciencesCovers the principles, methodologies and technologies of biopharmaceutics and pharmacokineticsFocus on pharmaceutical sciences, but also encompasses aspects of toxicology, neuroscience, environmental sciences, and nanotechnology INDICE: 1. Routes of administrations and implication on drug bioavailability2. Biopharmaceutics and Pharmacokinetics considerations in drug research3. Bioavailability and bioequivalence research in Product Development4. Pharmacokinetic characterization of drugs and new product designing5. Pharmacokinetic Modulation with Particulate Drug Formulations6. Dose, Dosage regimen and Dose adjustment7. Implications of Bio-Nanotechnology in neuroscience, tissue engineering and cancer therapy8. Physiologic pharmacokinetics models: Application and limitations9. Chronopharmacokinetics in drug design10. Drug toxicity and forensic pharmacokinetics11. Recent advancements in Pharmacogenomics12. Biocompatibility testing of biomaterials and biologicals13. Metabolic kinetics14. Animal handling and ethical considerations15. Biopharmaceutic and pharmacokinetic aspects of controlled release systems16. Degradation of biomaterials in biological environment17. Safety and long term toxicity evaluation of polymers used in Pharmaceutical Product Development: Regulatory considerations18. Toxicity and toxicokinetic consideration in product development and drug research19. Environmental and safety aspects of bio-nanotechnology20. Toxicity considerations on repetitive accumulation of polymeric materials
- ISBN: 978-0-12-814425-1
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 575
- Fecha Publicación: 01/11/2020
- Nº Volúmenes: 1
- Idioma: Inglés