Sensing the environment: regulation of local and global hemeostasis by the skin neuroendocrine system

Described as the body’s largest organ, the skin is strategically located at the interface with the external environment where it has evolved to detect, integrate and respond to a diverse range of stressors including solar radiation. A flurry of recent findings has established the skin as an important peripheral (neuro)endocrine organ that is tightly networked to central stress axes. This capability is contributing to the maintenance of skin homeostasis. Specifically, significant experimental evidence has gone on to show that epidermal cells produce and respond to classical stress neurotransmitters, neuropeptides and hormones, and that this production is stimulated by ultraviolet radiation, biological factors and other agents.

• ISBN: 978-3-642-19682-9
• Editorial: Springer
• Encuadernacion: Rústica
• Fecha Publicación: 27/07/2012
• Nº Volúmenes: 1
• Idioma: Inglés