Emerging Paradigms in Delivery of therapeutic agents for the Treatment of Glioblastoma

Emerging Paradigms in Delivery of Therapeutic Agents for the Treatment of Glioblastoma describes the intense research and clinical developments that are required to optimize the available treatment options and the potential side effects to heal brain cancer. The success of this strategy includes the use of validated biomarkers, appropriate patient selection criteria, strategies to prevent adverse events, and the implementation of immunotherapy in multimodal treatment approach. In 18 chapters, this title sets forth the rationales for promising therapies like immunotherapy, including immune checkpoint blockade, chimeric antigen receptor T (CAR T) cell therapy, oncolytic virotherapy, and vaccine therapy.In addition, the book reviews potential novel agents, the current status of preclinical and clinical trials, and the challenges and future perspectives in glioblastoma immuno-oncology. This book is a valuable resource for health professionals, scientists and researchers, health practitioners, students, and all those who wish to broaden their knowledge in the allied field. Helps to design and develop nanocarrier drug delivery systems and devices for the treatment of glioblastomaExplores a wide range of promising approaches for the diagnosis and treatment of glioblastoma using the latest advancement in cutting-edge nanomedical technologiesCovers recent advances and perspectives of novel drug delivery-based concepts for brain cancer researchIncludes recent patents and clinical trials in glioblastoma research, which will help fill in the gap between industries and academia INDICE: 1. Glioblastoma: Overview of the pathogenesis, clinical features, and diagnosis2. The challenges of brain tumour therapeutics, the future of brain tumour nanotherapeutics3. Role of Various Therapeutic Targets for in treatment of Glioblastoma4. Nanocarrier-Mediated Approaches and Conventional Therapies for Treatment Glioblastoma5. siRNA and miRNA-based strategies for management of Glioblastoma6. Lipid based nanocarrier(s) as Delivery Vehicles for Brain Tumour Therapy7. Polymeric Nanoparticulate Carrier for Brain Tumour Therapy8. Convection-Enhanced Delivery for Treatment of Glioblastoma9. Herbal approaches for treatment of glioblastoma10. Nanomedicine based photodynamic therapy for glioblastoma11. Thermoresponsive nanocarrier(s) based therapy for glioblastoma12. Peptide anchored nanocarrier(s) therapy for glioblastoma13. Theranostic applications of lipid-polymer based nanocarrier(s) for treatment of glioblastoma14. Targeting strategies in Gene Therapy for Glioblastoma15. Nanocarrier-based combination therapy for the treatment of glioblastoma16. Dendrimer assisted nanotechnological ways for glioblastoma drug delivery17. Inorganic/metallic nanoparticles in the treatment of glioblastoma18. Graphene Quantum Dots based Therapy for Glioblastoma

• ISBN: 978-0-443-33319-4
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 450
• Fecha Publicación: 01/03/2025
• Nº Volúmenes: 1
• Idioma: