Metabolomics is a multidisciplinary science used to understand the ways in which nutrients from food are used in the body and how this can be optimised and targeted at specific nutritional needs. Metabolomics as a Tool in Nutrition Research provides a review of the uses of metabolomics in nutritional research. Chapters cover the most important aspects of the topic such as analysis techniques, bioinformatics and integration with other 'omic' sciences such as proteomics and genomics. The final chapters look at the impact of exercise on metabolomic profiles and future trends in metabolomics for nutrition research. INDICE: Preface Part I Principles 1 Challenges in nutritional metabolomics: from experimental design to interpretation of data set M. Ferrara and J.-L. Sébédio, Institut National de la Recherche Agronomique (INRA), France 2 Metabolomic profiling as a tool in nutritional research: key methodological issues S. E. Richards, Nottingham Trent University, UK and E. Holmes, Imperial College, UK 3 Chemometrics methods for the analysis of genomics, transcriptomics, proteomics, metabolomics and metagenomics datasets S. E. Richards, Nottingham Trent University, UK and E. Holmes, Imperial College, UK Part II Applications in nutrition research 4 Application of lipidomics in nutrition research X. Han, Sanford-Burnham Medical Research Institute, USA and Y. Zhou, Chinese Academy of Sciences, P. R. China 5 Analysing human metabolic networks using metabolomics: understanding the impact of diet on health N. Poupin and F. Jourdan, Institut National de la Recherche Agronomique (INRA), France 6 Using metabolomics to analyse the role of gut microbiota in nutrition and disease G. Xie and W. Jia, University of Hawaii Cancer Center, USA 7 Metabotyping: moving towards personalized nutrition L. Brennan, UCD Institute of Food and Health, UK and Newcastle University, UK 8 Using metabolomics to identify biomarkers for metabolic diseases: analytical methods and applications J.-L. Sébédio and S. Polakof, Institut National de la Recherche Agronomique (INRA), France and Clermont Université, France 9 Using metabolomics to evaluate food intake: applications in nutritional epidemiology C. Manach, Institut National de la Recherche Agronomique (INRA), France, L. Brennan, UCD Institute of Food and Health, UK and Newcastle University, UK, and L. O. Dragsted, University of Copenhagen, Denmark 10 Metabolomics and nutritional challenge tests: what can we learn? L. Brennan, UCD Institute of Food and Health, UK and Newcastle University, UK 11 Using metabolomics to describe food in detail F. Capozzi and A. Trimigno, University of Bologna, Italy 12 Future perspectives for metabolomics in nutrition research: a nutritionist's view M. Ferrara, Institut National de la Recherche Agronomique (INRA), France
- ISBN: 978-1-78242-084-2
- Editorial: Woodhead Publishing
- Encuadernacion: Cartoné
- Páginas: 284
- Fecha Publicación: 19/12/2014
- Nº Volúmenes: 1
- Idioma: Inglés