Cell Movement in Health and Disease brings the several scientific domains related to the phenomena together, establishing a consistent foundation for researchers in this exciting field. The content is presented in four main section. The first explores the foundations of Cell Movement, including overviews of cellular structure, signaling, physiology, motion-related proteins, and the interface with the cellular membrane. The second part covers the biological aspects of cellular movement, starting with chemical and mechanical sensing, describing the types of cell movement, mechanics at cell level, cell physiology, collective behavior, and the connections with the extracellular matrix. The following chapters provide an overview of the molecular machinery involved and cell-type specific movement. The third part of the book is dedicated to the translational aspects of cell movement, highlighting the key conditions associated with cell movement dysfunction, like cell invasion in cancer, wound healing, developmental issues, neurological dysfunctions, and immune response. The final part of the book covers key methods and modeling tools for cell movement research, including predictive mathematical models, in vitro and in vivo methods, biophysical and bioinformatics tools. Cell Movement in Health and Disease is the ideal reference for scientists from different backgrounds converging to expand the understanding of this key cellular process. Cellular and molecular biologists will gain a better understanding of the physical principals operating at cellular level while biophysicist and biomedical engineers will benefit from the solid biology foundation provided by the book. Combines Biology, Physics and Modeling of cellular movement in one single source Updated with the current understanding of the field Includes key research methods for cell movement investigation Cover translational aspects of cellular movement INDICE: Section 1: Cell biological aspects of cell movement1. Cell structure and physiologyWANYU ZHAO, WEIDA REN, DICHUN HUANG, YUAN SANG, LINGBO CAO, AND JUNQI HUANG2. Migrasome in cell movement: new horizon for cell signalingDICHUN HUANG, RUFEI LIN, SHUCHEN LIU, HENGYI ZHONG, ZHANGSHUAI DAI, AND JUNQI HUANG3. Cellular substructures, actin dynamics, and actin-binding proteins regulating cell migrationNATHANIEL L. LARTEY AND MICHAEL SCHNOOR4. Impact of cell-cell interactions on communication and collectivenessJAZMIN ESPINOSA-RIVERO, CECILIA BANUELOS, AND ABIGAIL BETANZOS5. Cell migrationYUAN-NA LIN AND ANTON WELLSTEINSection 2: Mechano-biological aspects of cell movement6. Fundamental mechanics of cell shape and cell movementYIZENG LI AND SEAN X. SUN7. Extracellular matrixedependent mechanosensing and mechanotransduction: role in cell migrationNATASHA BUWA AND NAGARAJ BALASUBRAMANIAN8. Cellematrix interactions, force transmission, and mechanosensationCHRISTOPHER WALTER, HANNAH ZMUDA, JOSE A. ALMEIDA, AND AMIT PATHAKSection 3: Translational aspects of cell movement9. Cell movement during developmentWEN-CHAO TANG10. Cell migration in cardiovascular diseasesJENEFA BEGUM, SAMUEL R.C. WEAVER, ASIF J. IQBAL, G. ED RAINGER, AND HELEN M. MCGETTRICK11. Leukocyte movement during immune responsesEDUARDO VADILLO12. Migrasomes: the brightest? stars in cardiovascular system?ZHANG YAXING, LIU WEI, LIU HAIMEI, ZHOU LEQUAN, YAN FUMAN, GUAN LI, AND XU JINWEN13. Leukocyte trafficking to the intestinal barrier in health and diseaseGUSTAVO MONASTERIO, FRANCISCA A. CASTILLO, AND EDUARDO J. VILLABLANCA14. Cell movement and respiratory diseasesZHI-YING LV, QI MENG, AND LEI-MIAO YIN15. Cancer cell development, migratory response, and the role of the tumor microenvironment in invasion and metastasisINES M. ANTON, FRANCISCO WANDOSELL, AND MIGUEL VICENTE-MANZANARESSection 4: Methods and modeling tools for cell movement research16. Microfluidic tools to study cell migrationROBERTO RODRIGUEZ-MONCAYO, ALAN M. GONZALEZ-SUAREZ, ORESTES LO´ PEZ-ORTEGA, AND JOSE L. GARCIA-CORDERO17. Using real-time cell analysis to measure cell contractionDONG-DONG ZHOU, JIN LU, AND LEI-MIAO YIN18. Advanced microscopy techniques for the visualization and analysis of cell behaviorsDANIEL MERENICH, KATHLEEN E. VAN MANEN-BRUSH, CHRISTOPHER JANETOPOULOS, AND KENNETH A. MYERS19. Intravital microscopyIDAIRA M. GUERRERO FONSECA, MICHAEL SCHNOOR, AND EDUARDO VADILLO20. Mathematical and bioinformatic tools for cell trackingPETER HIRSCH, LEO EPSTEIN, AND LEO GUIGNARD
- ISBN: 978-0-323-90195-6
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 384
- Fecha Publicación: 13/04/2022
- Nº Volúmenes: 1
- Idioma: Inglés