Basic pharmacokinetics and pharmacodynamics: an integrated textbook and computer simulations

With its clear, straightforward presentation, this text enables you to grasp all the fundamental concepts of pharmacokinetics and pharmacodynamics. The text features guided exercises based on interactive computer models via its companion website, allowing you conduct simulations to bring drug effects to life and observe in real time how responses are affected by model parameters, and different dosing regimens. By presenting integrated pharmacokinetic and pharmacodynamic models, author Sara Rosenbaum describes how classic receptor theory and basic pharmacology have been applied to create therapeutically useful modelsfor indirect drug effects, tolerance, signal transduction, irreversible drug effects and disease progression You'll find several features throughout the text to help you better understand and apply key concepts in practice: Three fictitious drugs are used throughout the text to progressively illustrate the development and applications of pharmacokinetic and pharmacodynamic principles. Exercises at the end of each chapter provide the opportunity to perform pharmacokinetic evaluations and solve common dosing problems using your newfound knowledge and skills. Detailed instructions let you create custom Excel worksheetsto perform simple pharmacokinetic analyses Because this is an introductory textbook, the material is presented as simply as possible. As a result, you'll find it easy to gain an accurate, working knowledge of all the core principles and mathematics of pharmacokinetics and pharmacodynamics. Moreover, the many exercises and computer simulations will allow you to apply your knowledge and enhance your understanding of the material. This aspect of the book makes it ideal for self-study.

• ISBN: 978-0-470-56906-1
• Editorial: John Wiley & Sons
• Encuadernacion: Rústica
• Páginas: 438
• Fecha Publicación: 06/05/2011
• Nº Volúmenes: 1
• Idioma: Inglés