Key Chiral Auxiliary Applications, Second Edition is a detailed compilation of chiral auxiliary applications organized by type of transformation. Continuing from the most important and relevant auxiliaries described in its predecessor, the three-volume set Compendium of Chiral Auxiliary Applications (2001), as well as advances in the field, the book provides a vital and timely resource for chemists in the field. Each reaction class includes a series of tables and graphical abstracts of real reactions from the literature and patents to enable easy review and comparison of results. This anticipated edition is based on a screening of nearly 40,000 auxiliary reaction applications, with details supplied for the more than 13,000 selected representative entries: synthetic route, reagents, yields, diastereomeric/enantiomeric excesses, and characterization data. Updated and streamlined with more than 60% new material, Key Chiral Auxiliary Applications provides valuable guidance and reliable content for selecting the best auxiliary for a specific asymmetric synthetic transformation. Provides a comprehensive compilation based on nearly 40,000 diverse applications of chiral auxiliaries for selecting the best synthetic route to optically pure compoundsContains over 60% new material with 13,000+ auxiliary applications categorized by reaction type, with reaction details and chemical and optical yields in one unique resource INDICE: Chapter 1 - IntroductionSection A - SUBSTITUTION RELATED PROCESSESChapter 2 - Alkylation and Related Reactions IChapter 3 - Alkylation and Related Reactions IIChapter 4 - Alkylation and Related Reactions IIIChapter 5 - Alkylation and Related Reactions IVSection B - ADDITION TO UNSATURATED SYSTEMSChapter 6 - Electrophilic Related Addition To C=CChapter 7 - Conjugate Addition IChapter 8 - Conjugate Addition IIChapter 9 - Conjugate Addition IIIChapter 10 - Addition To C=N BondsChapter 11 - Addition To C=O Bonds IChapter 12 - Addition To C=O Bonds IIChapter 13 - Addition To C=O Bonds IIISection C - PERICYCLIC AND RELATED REACTIONSChapter 14 - Cycloadditions IChapter 15 - Cycloadditions IIChapter 16 - RearrangementsSection D - MISCELLANEOUS PROCESSESChapter 17a - Kinetic Resolution-Related ReactChapter 17b - Miscellaneous Reactions
- ISBN: 978-0-12-417034-6
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 1270
- Fecha Publicación: 21/02/2014
- Nº Volúmenes: 1
- Idioma: Inglés