This book covers topics on biochemically relevant organofluorine compounds and their synthesis and mechanistic pathways. Organofluorine compounds have renewed interest in pharmaceutical industry, and therefore a concise book on this topic is highly relevant to the scientific community involved in this area. Covers the synthesis, biochemical and therapeutic applications of organo fluorine compoundsLists all FFDA approved fluorine based therapeuticsContains active structures and Gaussian program to calculate the structure characteristics of all compoundsExplains the mechanistic of all biochemical reactions INDICE: Physicochemical characteristics of organofluorine compoundsGeneral mechanistic aspects of the biochemically significant organofluorine compoundsSpectroscopic techniques for characterization of organofluorine compoundsSynthetic methodologiesFluorinated organic compounds as mechanism based enzyme inhibitorsFluorinated amino acidsFluorinated CarbohydratesFluorinated peptide isosteresOrganofluoro compounds in pharmaceuticalsOrganofluoro compounds as anaestheticsOrganofluoro compounds in medical diagnostics and as tracers in biological mechanismsOrganofluro compounds in Neurological disorders and pathologies related to oxidative stressOrganofluoro compounds as anticancer agentsOrganofloro compounds as antibacterial and antiviral agents
- ISBN: 978-0-444-53748-5
- Editorial: Elsevier
- Encuadernacion: Rústica
- Páginas: 310
- Fecha Publicación: 01/02/2015
- Nº Volúmenes: 1
- Idioma: Inglés