An emerging field at the interface of biology and engineering, mechanobiology explores the mechanisms by which cells sense and respond to mechanical signals and holds great promise in one day unravelling the mysteries of cellular and extracellular matrix mechanics to cure a broad range of diseases. Mechanobiology: Exploitation for Medical Benefit presents a comprehensive overview of principles of mechanobiology, highlighting the extent to which biological tissues are exposed to the mechanical environment, demonstrating the importance of the mechanical environment in living systems, and critically reviewing the latest experimental procedures in this emerging field. Featuring contributions from several top experts in the field, chapters begin with an introduction to fundamental mechanobiological principles; and then proceed to explore the relationship of this extensive force in nature to tissues of musculoskeletal systems, heart and lung vasculature, the kidney glomerulus, and cutaneous tissues. Examples of some current experimental models are presented conveying relevant aspects of mechanobiology, highlighting emerging trends and promising avenues of research in the development of innovative therapies. Timely and important, Mechanobiology: Exploitation for Medical Benefit offers illuminating insights into an emerging field that has the potential to revolutionise our comprehension of appropriate cell biology and the future of biomedical research. INDICE: The Introduction will demonstrate mechanobiology is an extensive force in nature. Following chapters will be split into contributions based on tissue (bone, vascular etc). Within each chapter the contributor will develop the mechanobiology theme and speculate on pharmaceutical or physical activity to regulate mechanobiology as a site for medical intervention. Finally, a summing up chapter will pull together the threads of each of the preceding chapters to convey the relevant aspects to the reader. .Working Table of Contents or Outline of contents .Introduction Bone and musculoskeletal systems Vascular systems The Lung The Kidney The Senses Concluding Chapter
- ISBN: 978-1-118-96614-3
- Editorial: Wiley–Blackwell
- Encuadernacion: Cartoné
- Páginas: 400
- Fecha Publicación: 12/01/2017
- Nº Volúmenes: 1
- Idioma: Inglés