This book provides an integrated and comprehensive overview of modern approaches to lead discovery. Numerous refinements of established lead discovery methods have emerged over recent years, together with the introduction of a range of new approaches. Consequently, the rapidly changing and increasingly multidisciplinary lead discovery process poses a significant challenge to pharmaceutical professionals in terms of keeping up-to-date with the latest developments and fully understanding the capabilities and limitations of new technologies in order to be able to effectively apply them. Each chapter in this book reviews the theoretical background and application of a key technology in drug discovery, complemented by relevant case studies. The authors include leading scientists and established opinion leaders in drug discovery.Zoran Rankovic is Assistant Director for Medicinal Chemistry with Schering-Plough Corporation. He has over 13 years experience in drug discovery from target identification through hit / lead optimization. Dr. Rankovic has authored 27peer-reviewed journal articles, 9 issued or filed patents, 10 conference / oral presentations, and 2 book chapters. Richard Morphy is a medicinal chemist with Schering-Plough Corporation and has 20years in the pharmaceutical industry. He has been part of 6 presentations, 11 patents, and 35 journal articles.
- ISBN: 978-0-470-25761-6
- Editorial: Wiley
- Encuadernacion: Cartoné
- Páginas: 295
- Fecha Publicación: 29/03/2010
- Nº Volúmenes: 1
- Idioma: Inglés