Mononuclear Non-heme Iron Dependent Enzymes

Mononuclear Non-heme Iron Dependent Enzymes, Volume 703 focuses on methods for studying, characterizing, and leveraging the chemistry of mononuclear non-heme iron dependent enzymes. Chapters in this new release include Photoreduction for Rieske oxygenase chemistry, Insights into the Mechanisms of Rieske Oxygenases from Studying the Unproductive Activation of Dioxygen, Non-heme iron and 2-oxoglutarate enzymes catalyze cyclopropane and azacyclopropane formations, Obtaining precise metrics of substrate positioning in Fe(II)/2OG dependent enzymes using Hyperfine Sublevel Correlation Spectroscopy, Xe-pressurization studies for revealing substrate-entrance tunnels, and much more. Additional chapters cover A tale of two dehydrogenases involved in NADH recycling, Rieske oxygenases and/or their partner reductase proteins, Expression, assay and inhibition of 9-cis-epoxycarotenoid dioxygenase (NCED) from Solanum lycopersicum and Zea mays, Biocatalysis and non-heme iron enzymes, In vitro analysis of the three-component Rieske oxygenase cumene dioxygenase from Pseudomonas fluorescens IP01, Structure and function of carbazole 1,9a-dioxygenase, Characterization of a Mononuclear Nonheme Iron-dependent Mono-oxygenase OzmD in Oxazinomycin Biosynthesis, and much more. Provides detailed articles regarding how to study the structures and mechanisms of mononuclear non-heme iron dependent enzymesGuides readers on how to use partner proteins in non-heme iron enzyme catalysisIncludes strategies to employ mononuclear non-heme iron enzymes in biocatalytic applications INDICE: 1. Photoreduction for Rieske oxygenase chemistryPinghua Liu2. Insights into the Mechanisms of Rieske Oxygenases from Studying the Unproductive Activation of DioxygenThomas B. Hofstetter, Charlotte E. Bopp and Nora M. Bernet3. Non-heme iron and 2-oxoglutarate enzymes catalyze cyclopropane and azacyclopropane formationsWei-chen Chang4. Obtaining precise metrics of substrate positioning in Fe(II)/2OG dependent enzymes using Hyperfine Sublevel Correlation SpectroscopyAlexey Silakov5. Xe-pressurization studies for revealing substrate-entrance tunnelsJennifer D. Bridwell-Rabb6. A tale of two dehydrogenases involved in NADH recyclingJennifer D. Bridwell-Rabb7. Rieske oxygenases and/or their partner reductase proteinsPravindra Kumar8. Expression, assay and inhibition of 9-cis-epoxycarotenoid dioxygenase (NCED) from Solanum lycopersicum and Zea maysTimothy David Bugg9. Biocatalysis and non-heme iron enzymesXiongyi Huang10. In vitro analysis of the three-component Rieske oxygenase cumene dioxygenase from Pseudomonas fluorescens IP01Sandy Schmidt and Niels A.W. de Kok11. Structure and function of carbazole 1,9a-dioxygenaseHideaki Nojiri12. Characterization of a Mononuclear Nonheme Iron-dependent Mono-oxygenase OzmD in Oxazinomycin BiosynthesisHung-wen Liu13. Spectroscopic and computational studies of a bifunctional iron- and 2-oxoglutarate dependent enzyme, AsqJYisong Guo14. Non-heme iron oxygenases for natural product biosynthesisIkuro Abe15. Isonitrile Formation by a Non-Heme Iron(II)-Dependent Oxidase/DecarboxylaseWenjun Zhang16. Assays for the epidermal growth factor hydroxylase AsphChristopher Joseph Schofield17. Amino acid hydroxylasesPaul Fitzpatrick18. Extradiol dioxygenasesYifan Wang19. Title to be determinedRamaswamy Subramanian20. Experimental and computational approaches to understanding and addressing the stability limitations of Rieske OxygenasesJennifer DuBois21. Construction and Testing of Whole-Cell Non-Heme Iron BiocatalystsRyan Summers22. Equilibrium dialysis to measure binding affinities of non-heme iron enzymesAmbika Bhagi-Damodaran23. title to be determinedThomas C. Brunold24. Approaches to determination of the mechanism of the Rieske monooxygenase salicylate 5-hydroxylaseJohn D. Lipscomb and Melanie Rogers25. Preparation of reductases for multicomponent oxygenasesLindsay David Eltis and Megan Wolf26. Expression, purification, and biochemical characterization of micro- and macroalgal kainoid synthases Shaun McKinnie27. Title to be determinedKabirul Islam28. Title to be determinedEdward I. Solomon29. title to be detrminedAdam Offenbacher

• ISBN: 978-0-443-31304-2
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 412
• Fecha Publicación: 01/09/2024
• Nº Volúmenes: 1
• Idioma: Inglés