Retinoid Signaling Pathways, Volume 637, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Sections in this release include The chemistry and biochemistry of Vitamin A and its natural derivative, Biosynthesis of retinoic acids, Biodegration of retinoic acids mediated by retinoid binding proteins, Retinoic acid homeostasis, Cryo Electron Microscopy to study retinol update via the STRA6 receptor, Immuno-detection of retinoic acid synthesis enzymes in the brain, classical pathway of gene regulation by retinoids, Protein-protein interactions in the regulation of retinoid acid receptors activity, and much more. Provides the authority and expertise of leading contributors from an international board of authorsPresents the latest release in the Methods in Enzymology seriesIncludes the latest information on retinoid signaling pathways INDICE: 1. The chemistry and biochemistry of Vitamin A and its natural derivative Chris Redfern 2. Biosynthesis of retinoic acids Joseph L. Napoli 3. Biodegration of retinoic acids mediated by retinoid binding proteins Joseph L. Napoli 4. Retinoic acid homeostasis Natalia Kedishvili 5. Cryo Electron Microscopy to study retinol update via the STRA6 receptor Filippo Mancia 6. Immuno-detection of retinoic acid synthesis enzymes in the brain Peter McCaffery 7. Classical pathway of gene regulation by retinoids Ehmke Pohl 8. Protein-protein interactions in the regulation of retinoid acid receptors activity William Bourguet 9. Ligand binding of RXR receptors Angel R. de Lera 10. DNA recognition Natacha Rochel 11. Non-canonical retinoid signalling Li-Na Wei 12. Characterization of hepatic RXRalpha cells Yu-Jui Yvonne Wan 13. Analysis of vitamin A and retinoids in biological matrices Nina Isoherranen 14. In-vivo studies of retinoids Mary-Ann Asson Batres 15. Studying the role of retinoids in development Paul Trainor 16. Combining immunohistochemistry and in situ hybridization for studying retinoic acid signaling in developing amphioxus Michael Schubert 17. Design and synthesis of retinoids David Chisholm 18. Testing novel rexinoids using human skin raft cultures Natalia Kedishvili 19. Localisation of RAR active drugs Peter McCaffery 20. Assays development of fluorescent retinoids Andy Whiting 21. Future potential of retinoids in therapies A Catharine Ross
- ISBN: 978-0-12-820144-2
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 412
- Fecha Publicación: 01/05/2020
- Nº Volúmenes: 1
- Idioma: Inglés