Fundamentals of Molecular Structural Biology reviews the mathematical and physical foundations of molecular structural biology and, based on these fundamental concepts, utilizes later chapters to describe molecular structure and explain basic genetic mechanisms. Given the increasingly interdisciplinary nature of research, early career researchers and those shifting into an adjacent field often require a fundamentals book to get them quickly up to speed on the foundations of a particular field, and this volume fills that niche. Provides a current and easily digestible resource on molecular structural biology, discussing both foundations and the latest advancesAddresses critical issues surrounding macromolecular structures, such as structure-based drug discovery, single-particle analysis, computational molecular biology/molecular dynamic simulation, cell signaling and immune response, macromolecular assemblies, and systems biologyPresents discussions that ultimately lead the reader toward a more detailed understanding of the basis and origin of disease INDICE: 1. Introduction: A historical perspective2. Mathematical Tools3. Physical Basis of Chemistry4. Chemical Basis of Biology5. Biomolecules6. Structure analysis and visualization7. Protein Folding8. DNA Replication9. Transcription10. RNA processing11. Translation12. DNA Damage and Repair13. Recombination14. Membrane structure and function15. Fundamentals of Structural Genomics
- ISBN: 978-0-12-814855-6
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 500
- Fecha Publicación: 01/09/2019
- Nº Volúmenes: 1
- Idioma: Inglés