Chemistry and biochemistry of oxygen therapeutics: from transfusion to artificial blood

ÍNDICE: 1. Introduction (Richard B. Weiskopf). Part 1. Oxygen: chemistry, biochemistry, physiology and toxicity. 2. Hemoglobin Reactivity and Regulation (Stefano Bettati and Andrea Mozzarelli). 3. The Major Cellular and Physiological Control Mechanisms of Blood Flow and Oxygen Delivery (Raymond C. Koehler). 4. The Main Players: Hemoglobin and Myoglobin; Nitric Oxide and Oxygen (Tim J.McMahon and Joseph Bonaventura). 5. The Role of Reactive Oxygen and Nitrogen Species in Ischemia/Reperfusion Injury (Ester Spagnolli and Warren Zapol). Part 2. Medical needs for oxygen supply. 6. Acute Traumatic Hemorrhage and Anemia(Lena M. Napolitano). 7. Diagnosis and Treatment of Haemorrhages in 'Non-surgical' Patients (Umberto Rossi and Rosa Chianese). 8. Management of Perioperative Bleeding (Sibylle A. Kozek-Langenecker). 9. Oxygenation in the Preterm Neonate (Vidheya Venkatesh, Priya Muthukuma, Anna Curley and Simon Stanworth). 10.Ischemia (Hooman Mirzakhani and Ala Nozari). 11. Normobaric and Hyperbaric Oxygen Therapy for Ischemic Stroke and Other Neurological Conditions (Ari Moskowitz, Yu-Feng Yvonne Chan and Aneesh B. Singhal). 12. Transfusion Therapy in Thalassemia and Sickle Cell Disease (Carlo Brugnara and Lucia De Franceschi). Part 3. Oldand new strategies for oxygen supply. 13. Transfusion: Political, Administrative and Logistic Issues (John R. Hess and Giuliano Grazzini). 14. Conscientious Objection in Patient Blood Management (Kenneth E. Nollet and HitoshiOhto). 15. Red Cell Transfusion in Clinical Practice (Harvey G. Klein). 16. Causes and Consequences of Red Cell Incompatibility (Chisa Yamada and RobertsonDavenport). 17. Biochemistry of Red Blood Cell Storage (Ryan Stapley, Dario A. Vitturi and Rakesh P. Patel). 18. Proteomic Investigations on Stored Red Blood Cells (Lello Zolla and Angelo D'Alessandro). 19.Red Blood Cells from Stem Cells (Anna Rita Migliaccio, Carolyn Whitsett and Giovanni Migliaccio). 20. TheUniversal Red Blood Cell (Luca Ronda and Serena Faggiano). 21. Allosteric Effectors of Hemoglobin: Past, Present and Future (Martin K. Safo and Stefano Bruno). 22. Hemoglobin-based Oxygen Carriers: History, Limits, Brief Summary of the State of the Art, Including Clinical Trials (Jonathan S. Jahr, Arezou Sadighi, Linzy Doherty, Alvin Li and Hae Won Kim). 23. Oxygen Delivery by Natural and Artificial Oxygen Carriers (Enrico Bucci). 24. Cross-Linked and PolymerizedHemoglobins as Potential Blood Substitutes (Kenneth W. Olsen and Eugene Tarasov). 25. Design of Novel PEGylated Hemoglobins as Oxygen Carrying Plasma Expanders: Engineering the Structure of PEG-Hb Adducts for Supra Perfusion (Seetharama A. Acharya, Marcos Intaglietta, Amy G. Tsai, Kulal Ananda and Fantao Meng). 26. Hb Octamers by Introduction of Surface Cysteines Véronique (Baudin-Creuza, Chien Ho and Michael C. Marden). 27. Hemoglobin-vesicles as a Cellular TypeHemoglobin-based Oxygen Carrier (Hiromi Sakai, Hirohisa Horinouch

• ISBN: 978-0-470-68668-3
• Editorial: John Wiley & Sons
• Encuadernacion: Cartoné
• Páginas: 480
• Fecha Publicación: 12/08/2011
• Nº Volúmenes: 1
• Idioma: Inglés