Managing the Drug Discovery Process: How to Make It More Efficient and Cost-Effective

Managing the Drug Discovery Process: How to Make It More Efficient and Cost-Effective thoroughly examines the current state of pharmaceutical research and development (R&D) from research, development, and business perspectives. Since drug research can be a high-risk, high-payoff industry, it is important for researchers to effectively and strategically manage the drug discovery process. This book takes a closer look at increasing pre-approval costs for new drugs and examines not only why these increases occur, but also how they can be overcome to ensure a robust pharmacoeconomic future. The book also considers the interplay of stakeholders, consumers, and the drug firm with attendant factors, including those that are technical, legal, economic, demographic, political, social, ecological, and infrastructural. Aimed at redirecting the drug discovery process to make it more efficient and cost-effective, this book is a valuable and compelling resource for researchers and postgraduate students in academia and the pharmaceutical industry. Considers drug discovery in multiple R&D venues, including big pharma, large biotech, start-up ventures, academia, and nonprofit research institutesAnalyzes the organization of pharmaceutical R&D, taking into account human resources considerations like recruitment and configuration, management of discovery and development processes, and the coordination of internal research within, and beyond, the organization, including outsourced workPresents a consistent, well-connected, and logical dialogue that readers will find both comprehensive and approachable INDICE: 1. Organizational Aspects Introduction Major Issues Including Attrition Project Management Including Teams Recruitment and Management of Human Resources Multiple Sites Including Outsourcing Contrasting Biotech with Pharma and Innovation Business Development Including Aspects of Portfolio Management  Drug Development 2. Drug Discovery Introduction Technologies Chemical Biology and Chemical Genomics From Small Molecules to Macromolecules Computational Approaches Evolution of Preclinical Research over Several Decades Transition from Research to Development Including ADMET The Perspective of Successful Drug Hunters 3. Targets Introduction  Project Selection Target Classes References

• ISBN: 978-0-08-100625-2
• Editorial: Woodhead Publishing
• Encuadernacion: Cartoné
• Páginas: 256
• Fecha Publicación: 01/11/2016
• Nº Volúmenes: 1
• Idioma: Inglés