Reproducibility in Biomedical Research: Epistemological and Statistical Problems and the Future

Reproducibility in Biomedical Research: Epistemological and Statistical Problems, Second Edition explores the ideas and conundrums inherent in scientific research. This second edition addresses new challenges to reproducibility in biosciences, namely reproducibility of machine learning Artificial Intelligence (AI), reproducibility of translation from research to medical care, and the fundamental challenges to reproducibility. All current chapters are expanded to cover advances in the topics previously addressed. This book provides biomedical researchers with a framework to better understand the reproducibility challenges in the area. Newly introduced interactive exercises and updated case studies help students understand the fundamental concepts involved in the area. Includes four new chapters and updates across the book, covering recent developments of issues affecting reproducibility in biomedical researchCovers reproducibility of results from machine learning AI algorithmsPresents new case studies to illustrate challenges in related fieldsIncludes a companion website with interactive exercises and summary tables INDICE: 1. Introduction2. The Problem of Irreproducibility3. Validity of Biomedical Science, Reproducibility, and Irreproducibility4. The Logic of Certainty versus the Logic of Discovery5. The Logic of Probability and Statistics6. Causation, Process Metaphor, and Reductionism7. Case Studies in Clinical Biomedical Research 8. Case Studies in Basic Biomedical Research9. Case Studies in Computational Biomedical Research10. Case Studies in Machine Learning Artificial Intelligence (AI)11. Reproducibility of translation from biomedical research to clinical care12. Chaotic and Complex Systems, Statistics, and Far-from-Equilibrium Thermodynamics13. The Nature of the Fundamental Challenges to Reproducibility in any Knowledge Discipline14. Epilogue15. Appendix: Types of lack of reproducibilityility

• ISBN: 978-0-443-13829-4
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 464
• Fecha Publicación: 26/04/2024
• Nº Volúmenes: 1
• Idioma: Inglés