Human Organs-on-a-Chip Technology focuses on technology advancement from “organ-on-a-chip”, “multi organs-on-a-chip”, and the newest stage of “human organs-on-a-chip. Chapters investigate the design, simulation studies, device development, and application of microfluidic systems. In addition, they offer expert perspectives on the development of an alternative test system in the biological evaluation of drugs, cosmetics, chemicals, medical devices, and many others. Lastly, the book addresses issues related to the development of microfluidic devices and alternative test systems in biological and biomedical research. Explores organs-on-a-chip technology, from the basics, to advanced developments and existing challenges and recent research trends and applicationsReviews every aspect of microfluidic devices, including biological evaluation and targeted deliveryIncludes the latest information on regulatory updates INDICE: 1. Basics of Microfluidics technology2. The Physics and Engineering of Flow in Organ on a Chip Devices3. Importance of Soft lithography4. Development of microfluidic devices5. Microfluidics based point of care devices6. Microfluidics, Organs-on-a-chip and 3D printing7.Microfluidic platforms: applications and challenges8. Design and simulation study of Organ-on-a-chip9. Primary Cell culture for Organ-on-a-chip10. Vascularisation in organs-on-a-chip11. Organ-on-a-chip in nanotechnology12. Organs-on-a-chip in precision medicine13. Foeto-placental organ-on-a-chip14. Organs-on-a-chip in drug development15. Organ-on-a-chip for multianalyte monitoring16. Organ-on-a-chip for Blood-brain-barrier studies17. Organs on a chip models for sensor18. Innovative ‘organs-on-a-chip’ technology for marine drug development19. Exposure-on-a-chip as a model for inhalation toxicology and pharmacology research20. Brain-on-chip21. Recent breakthrough in organ-on-a-chip22. 3D printed microfluidic chips23. 3D tissue and Organ-on-a-chip models24. Vascularisation of organoids in microfluidic chips25. Multiorgans-on-a-chip: Design and applications26. Multiorgans-on-a-chip for subacute toxicity27. Multiorgans-on-a-chip for acute toxicity28. Human organs-on-a-chip for biological evaluation29. Human organs-on-a-chip for cancer modelling
- ISBN: 978-0-443-13782-2
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 628
- Fecha Publicación: 18/06/2024
- Nº Volúmenes: 1
- Idioma: Inglés