Population Genomics in the Developing World: Concepts, Applications, and Challenges

Population Genomics in the Developing World: Concepts, Applications, and Challenges, a new volume in the Translational and Applied Genomics series, provides a comprehensive, up-to-date summary of the field of population genomics in developing countries. The book equips students, researchers, and clinicians with the practical skills and approaches necessary to face the unique challenges and opportunities of practicing population genomics in developing countries. Following a brief foundational overview, more than a dozen authors working in developing nations share applied case studies from the field, including rationale, methods, analysis, and outcomes to reinforce understanding. Key themes across the country specific chapters include efficient genetic data generation and effective computational and statistical tools to analyze population-level data. The book then discusses clinical interpretation of this data, from direct-to-consumer ancestry testing to translational and applied precision medicine. A final chapter considers ethical aspects of conducting genomic research in developing countries. Addresses the unique opportunities to positively impact global health by practicing population genomics in developing countriesFeatures applied case studies from genomic research in various developing nations, with clear instruction in research rationale, methods, tools, materials used, analysis, and outcomesFeatures international chapter authors and population genomics experts practicing in South Africa, Gabon, India, South America, Central America, and Honduras, among other locations INDICE: 1. Population genomics - the fundamentals2. Why focus on population genomics in developing countries?3. History of population genomics in developing countries4. Latest developments and trends in the field of population genomics research5. Field work in developing countries6. Genotyping and sequencing technologies: access in developing countries7. Computational tools and statistical approaches8. Genotype versus phenotype versus environment9. Direct-to-consumer genetic testing and the population genomics industry10. Translating research to clinical utility - personalised medicine11. Ethical issues in population genomics and impact on clinical implementation12. Research uptake in developing countries and the role of various stakeholders13. The future of population genomics in developing

• ISBN: 978-0-443-18546-5
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 472
• Fecha Publicación: 01/11/2024
• Nº Volúmenes: 1
• Idioma: Inglés