Pharmacogenetics and individualized therapy

INDICE: Preface (Dr A. H. Maitland-van der Zee and Dr A. K. Daly). 1.Pharmacogenetics: a historical perspective (Dr A. K. Daly). Pharmacogenetics: relationship to pharmacokinetics and pharmacodynamics. 2. Pharmacogenetics in drug metabolism: Role of Phase I enzymes (Dr V. Dolzan). 3. Pharmacogenetics of phase II drug metabolizing enzymes (Prof I. Cascorbi). 4. Pharmacogenetics of drugtransporters (Henriette E. Meyer zu Schwabedissne, Markus Grube, Prof. Heyo K. Kroemer). 5. Pharmacogenetics of drug targets (Dr M. Arranz and Prof A. Daly). Pharmacogenetics in different therapeutic areas. 6. Cardiovascular Pharmacogenetics (Bas J. M. Peters, Prof. Anthonius de Boer, Prof. Tom Schalekamp, Prof. H. Klungel, Anke-Hilse Maitland-van der Zee, PharmaD PhD). 7. Pharmacogenetics in psychiatry (Evangelia M. Tsapakis, Sarah Curran, Ruth I. Ohlsen, Nora S. Vyas, Ann K. Daly, Katherine J. Aitchison). 8. Pharmacogenetics in cancer (Dr S. Marsh). 9. Pharmacogenetics of Asthma and COPD (E. Koster, Dr G. H. Koppelman, Dr J.A. M. Raaijmakers, Dr A. H. Maitland-van der Zee). 10. Pharmacogenetics of adverse drug reactions (Prof. Ann K. Daly, Dr. Martin Armstrong and Prof. Munir Pirmohamed). 11. Pharmacogenomics of inflammatory bowel diseases (Dr. Alexander Teml, Dr. Susanne Karner, Dr. Elke Schaeffeler, Prof. Matthias Schwab). 12. Pharmacogenetics of pain medication (Dr. J. Loetsch). Pharmacogenetics: implementation in clinical practice. 13. Ethical and social issues in pharmacogenetics testing (S. Vijverberg, Dt T. Pieters and Dr M. Cornel). Developments in Pharmacogenetic Research. 14. High-throughput genotyping technologies for pharmacogenetics (Beatriz Sobrino and Dr. Angel Carracedo). 15. Developments in analyses in pharmacogenetic datasets (Dr A. Motsinger). Pharmacogeneticsin industry and in regulatory affairs. 16. Applications of Pharmacogenetics in Pharmaceutical Research and Development (Dr. Daniel K. Burns and Dr. Scott S. Sundseth). 17. Role of Pharmacogenetics in Registration Process (Dr. Myong-Jin Kim, Dr. Issam Zineh, Dr. Shiew-Mei Huang, and Dr. Lawrence J. Lesko). Conclusions. 18. Pharmacogenetics: possibilities and pitfalls (Dr A. H. Maitland-van der Zee and Dr A. K. Daly).

• ISBN: 978-0-470-43354-6
• Editorial: John Wiley & Sons
• Encuadernacion: Cartoné
• Páginas: 440
• Fecha Publicación: 30/11/2011
• Nº Volúmenes: 1
• Idioma: Inglés