Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry. This volume continues in the serial's tradition of providing an insight into the skills required of the modern medicinal chemist; in particular, the use of an appropriate selection of the wide range of tools now available to solve key scientific problems, including g-secretase modulators, P2X7 antagonists as therapeutic agents for CNS disorders, N-type calcium channel modulators for the treatment of pain, and more. Extended timely reviews of topics in medicinal chemistryTargets and technologies relevant to the discovery of tomorrow's drugs.Analyses of successful drug discovery programmes INDICE: Structure Based Drug Design for G Protein-Coupled Receptors Miles Congreve, João M. Dias and Fiona H. Marshall P2X7 Antagonists as Potential Therapeutic Agents for the Treatment of CNS Disorders Christa C. Chrovian, Jason C. Rech, Anindya Bhattacharya and Michael A. Letavic g-Secretase Modulators: Current Status and Future Directions Adrian Hall and Toshal R. Patel Recent Progress in the Discovery and Development of N-Type Calcium Channel Modulators for the Treatment of Pain Margaret S. Lee
- ISBN: 978-0-444-63380-4
- Editorial: Elsevier
- Encuadernacion: Cartoné
- Páginas: 216
- Fecha Publicación: 31/01/2014
- Nº Volúmenes: 1
- Idioma: Inglés