Advancement of Phenolic Acids in Drug Discovery: Fundamentals and Applications

Advancement of Phenolic Acids in Drug Discovery: Fundamental and Applications offers comprehensive coverage of the ADMET profiles of phenolic acids, their extraction method and prospects for drug design and development. Chapters overview phenolic acids and their characterization, discuss the role of phenolic acids in plant systems, present sources and detailed extraction methods of phenolic acids, and cover phenolic acid mechanisms of action as it relates to several key diseases and health conditions, including their role as antioxidant agents, anti-inflammatory and analgesic drugs, anti-microbial drugs, anti-viral drugs, anti-cancer drugs, diabetes and metabolic dysfunctions, neurological disorders, cardiovascular diseases. The book's final chapters cover nanoscience aspects of phenolic acids, biomedical applications, and concludes with challenges and opportunities presented by phenolic acids. This is the ideal reference for researchers in the fields of drug development, both in academia and corporate settings. Researchers of related areas like food science and medicinal chemistry will also benefit from this in-depth profiling of therapeutical properties of phenolic acids. Highlights fundamental concepts with advanced exploration of phenolic acidsProvides in-depth coverage on the design and development of novel drugs from natural phenolic acidsReviews the changing role of phenolic acids INDICE: 1. Phenolic acids: A Brief Overview2. Sources and extraction methods of phenolic acids3. Role of phenolic acids in plant system4A. Antioxidant methods, in vitro and in vivo studies of phenolic acids4B. Phenolic acids as potent antioxidant agents5. Phenolic acids based anti-inflammatory and analgesic drugs6. Progressive approach of phenolic acids towards the advancement of antimicrobial drugs7. Promising role of phenolic acids as antimalarial and antiviral drugs8. Development of phenolic acids-based system as anticancer drugs9. Utility of phenolic acids in neurological disorders10. Role of aronia`s phenolic acids in the treatment of diabetes mellitus11. Phenolic acids in cardiovascular cure and treatment12. Development of phenolic acids based nanocarriers and nanomedicines13. Valorization of phenolic compounds delivery through lactic acid fermentation of fruit and vegetable juices: Innovations, challenges and gaps14. Development of metal-phenolic acid network for biomedical usages15. Grand challenges and opportunities for phenolic acids

• ISBN: 978-0-443-18538-0
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 538
• Fecha Publicación: 28/06/2024
• Nº Volúmenes: 1
• Idioma: Inglés