The near-field region within an order of 100 nm from the solid interface is an exciting and crucial arena where many important multiscale transport phenomena are physically characterized, such as flow mixing and drag, heat and mass transfer, near-wall behavior of nanoparticles, binding of bio-molecules, crystallization, surface deposition processes, just naming a few. This monograph presents a number of label-free experimental techniques developed and tested for near-field fluid flow characterization. Namely, these include Total Internal Reflection Microscopy (TIRM), Optical Serial Sectioning Microscopy (OSSM), Surface Plasmon Resonance Microscopy (SPRM), Interference Reflection Contrast Microscopy (IRCM), Thermal Near-Field Anemometry, Scanning Thermal Microscopy (STM), and Micro-Cantilever Near-Field Thermometry. Presentation on each of these is laid out for the working principle, how to implement the system, and its example applications, to promote the readers understanding and knowledge of the specific technique that can be applied for their own research interests. Presents a number of label-free experimental techniques. Presentation on each technique is laid out for the working principle. Written for experts in this field. INDICE: Introduction. Definitions of near-field. Evanescent wave penetration depth. Surface. Photon penetration skin-depth into metal. Penetration depthof no-slip boundary conditions. Equilibrium height for small particles under near-field forces. Total Internal Reflection Microscopy (TIRM). Ratiometric TIRM imaging analysis. Near-field applications of TIRM. Near-wall hindered Brownian motion of nanoparticles. Slip-flows in the near-field. Cytoplasmic viscosity and intracellular vesicle sizes. Optical Serial Sectioning Microscopy (OSSM). Point spread functions (PSFs) under aberration-free design conditions. Point spread functions (PSFs) under off-design conditions. Principles of OSSM. Near-field applications of OSSM. Three-dimensional particle tracking velocimetry (PTV). Near-wall thermometry. Near-field mixture concentration measurements. Confocal Laser Scanning Microscopy (CLSM). Principles of confocal imaging. Microscopic imaging resolutions. Confocal microscopic imaging resolutions. Opticalslicing thickness of confocal microscopy. Confocal laser scanning microscopicparticle imaging velocimetry (CLSM-PIV) system. Near-field applications of CLSM-PIV. Poiseuille flows in a microtube. Microscale rotating Couette flows. Moving bubbles in a microchannel. Surface Plasmon Resonance Microscopy (SPRM). Surface plasmon polaritons (SPPs). Dispersion of SPP. Kretschmann’s three-layerconfiguration. Surface plasmon resonance (SPR) reflectance. Surface plasmon resonance microscopy (SPRM) imaging systems. Selection of a prism for SPRM. SPRreflectance imaging resolution. Near-field applications of SPRM. History and uses of SPRM. Label-free mapping of microfluidic mixing fields. Near-field mapping of salinity diffusion. Dynamic monitoring of nanoparticle concentration profiles. Unveiling the fingerprints of nanocrystalline self-assembly. Near-wall thermometry. Reflection Interference Contrast Microscopy (RICM). Interference of plane waves. Principles and practical issues of RICM. Near-field applications of RICM. Thin-film thickness measurements. Electrohydrodynamic (EHD) control of thin liquid film. Dynamic fingerprinting of live-cell focal contacts. References.
- ISBN: 978-3-642-20425-8
- Editorial: Springer Berlin Heidelberg
- Encuadernacion: Cartoné
- Páginas: 148
- Fecha Publicación: 11/04/2011
- Nº Volúmenes: 1
- Idioma: Inglés