Dendrimer-Based Nanotherapeutics delivers a comprehensive resource on the use of dendrimer-based drug delivery. Advances in the application of nanotechnology in medicine have given rise to multifunctional smart nanocarriers that can be engineered with tunable physicochemical characteristics to deliver one or more therapeutic agent(s) safely and selectively to cancer cells, including intracellular organelle-specific targeting. This book compiles the contribution of dendrimers in the field of nanotechnology to aid researchers in exploring dendrimers in the field of drug delivery and related applications. This book covers the history of the area to the most recent research. The starting chapter covers detailed information about basic properties about dendrimers i.e. properties, nomenclature, synthesis methods, types, characterization of dendrimers, safety and toxicity issues of dendrimers. Further chapters discuss the most recent advancements in the field of dendrimer i.e. dendrimer-drug conjugates, PEGylated dendrimer, dendrimer surface engineering, dendrimer hybrids, dendrimers as solubility enhancement, in targeting and delivery of drugs, as photodynamic therapy, in tissue engineering, as imaging contrast agents, as antimicrobial agents, advances in targeted dendrimers for cancer therapy and future considerations of dendrimers. Dendrimer-Based Nanotherapeutics will help the readers to understand the most recent progress in the field of dendrimer based research, suitable for pharmaceutical scientists, advanced students, and those working in related healthcare fields. Discusses various routes such as oral, pulmonary, transdermal, delivery and local administration of dendrimer delivery of bioactiveExplores a wide range of applications of dendrimer-based drug delivery using the latest advancements in nanomedicineProvides the most recent research on dendrimers as well as context and background, providing a useful resource for all levels of researcher INDICE: 1. History and introduction of dendrimers 2. Properties of dendrimers 3. Biological interactions of dendrimers 4. Dendrimer nomenclature and synthesis methods 5. Types of dendrimers 6. Characterization of dendrimers 7. Safety and toxicity issues of dendrimers 8. Dendrimer-drug conjugate 9. PEGylated dendrimer 10. Surface engineered dendrimers in targeting and delivery of drugs 11. Dendrimer hybrids with other nanocarriers 12. Dendrimers for solubility enhancement 13. Dendrimers for gene therapy 14. Dendrimer for photodynamic therapy 15. Dendrimers in tissue engineering 16. Dendrimer as imaging contrast agents 17. Dendrimer as antimicrobial agents 18. Theranostic dendrimer for cancer 19. Dendrimer as anti-inflammatory prodrugs 20. Advances in targeted dendrimers for cancer therapy and challengesfor clinical translation 21. Conclusion and future considerations of dendrimers
- ISBN: 978-0-12-821250-9
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 445
- Fecha Publicación: 01/06/2021
- Nº Volúmenes: 1
- Idioma: Inglés