In this volume well known kinases are discussed and complemented with reviews about important, but often neglected kinases. A good representation of current model organisms from plants, C. elegans to mice are used as the basis to illustrate how we can use our understanding of normal development to learn about disease. Kinases are fundamental regulators of most biological processes and thus have key roles in development of all organismsConsequently, aberrant regulation of kinases causes severe diseasesBroad scope of topics addressedAllows researchers and newcomers to this research area to gain a thorough picture of the current knowledge INDICE: 1. WNK kinases in development and disease Aylin Rodan and Andreas Jenny 2. PI3K/Akt (Cancer, growth) Antonio Di Cristofano 3. Homeodomain-interacting protein kinases (Hipks): Diverse and complex roles in development and disease Esther M. Verheyen 4. ROR-family receptor tyrosine kinases Alexandra Schambony 5. Regulation of Drosophila Development by the Golgi Kinase Four-jointed Hiroyuki O. Ishikawa 6. Hippo/SWH pathway, cancer/ organ size Cathie Michelle Pfleger 7. Csf1R/ brain microglia E. Richard Stanley 8. GSK3/ (Wnt) Jim Woodget 9. CK1 in Developmental signaling: Hedgehog and Wnt Jin Jiang 10. Ligand-receptor mediated regulation of growth in plants Michael Sussman 11. Par1/ cell polarity Erik Griffin 12. receptor kinases and phosphatases in neural wiring Bassem Hassan 13. VGEFR/ Pvr in blood vessel formation Konstantin Gaengel
- ISBN: 978-0-12-801513-1
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 362
- Fecha Publicación: 01/04/2017
- Nº Volúmenes: 1
- Idioma: Inglés