Research and Clinical Applications of Targeting Gastric Neoplasms

Research and Clinical Applications of Targeting Gastric Neoplasms provides a comprehensive overview of gastrointestinal cancers, covering preclinical research and clinical findings related to risk factors, current treatment regimens (including immunotherapy), screening/detection methods, etiology of disease, precision medicine and future perspectives. Gastrointestinal cancers rank among the most lethal and common worldwide, and as such, there is intense research into their diverse causes and treatment options. This reference provides a consolidation of the research, making it a perfect resource for basic science and clinical researchers as well as oncologists who work in gastroenterology and GI tract cancer fields. Provides comprehensive coverage of preclinical research and the clinical aspects of gastric cancer Presents future perspectives from leading researchers in the field who provide the potential for furthering research topics Combines the expertise of researchers in GI tracts, cancer, immunity, immunology, infectious disease and microbiology for an interdisciplinary approach INDICE: 1. Stomach corpus stem cells in homeostasis, tissue repair, and cancer 2. The role of inflammation in gastric tumorigenesis 3. Unravelling the pro-tumorigenic role of innate immune pattern recognition receptors in the gastric compartment 4. Helicobacter pylori-induced gastric carcinogenesis 5. The role of Helicobacter pylori CagA oncoprotein in neoplastic transformation of gastric epithelial cells 6. Epigenetic aberrations by Epstein-Barr virus infection to develop gastric cancer 7. In vivo and in vitro models of gastric cancer 8. Premalignant lesions of the stomach and management of early neoplastic lesions 9. Updated perspective and directions on hereditary diffuse gastric cancer 10. Systems biology and molecular characterization of subtypes to guide targeted therapies in gastric cancer 11. Current state of chemotherapy and immunotherapy regimens in gastric cancer 12. Case studies highlighting the multiple facets of gastric cancer: one diagnosis, multiple approaches1. Stomach corpus stem cells in homeostasis, tissue repair, and cancer 2. The role of inflammation in gastric tumorigenesis 3. Unravelling the pro-tumorigenic role of innate immune pattern recognition receptors in the gastric compartment 4. Helicobacter pylori-induced gastric carcinogenesis 5. The role of Helicobacter pylori CagA oncoprotein in neoplastic transformation of gastric epithelial cells 6. Epigenetic aberrations by Epstein-Barr virus infection to develop gastric cancer 7. In vivo and in vitro models of gastric cancer 8. Premalignant lesions of the stomach and management of early neoplastic lesions 9. Updated perspective and directions on hereditary diffuse gastric cancer 10. Systems biology and molecular characterization of subtypes to guide targeted therapies in gastric cancer 11. Current state of chemotherapy and immunotherapy regimens in gastric cancer 12. Case studies highlighting the multiple facets of gastric cancer: one diagnosis, multiple approaches

• ISBN: 978-0-323-85563-1
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 370
• Fecha Publicación: 23/07/2021
• Nº Volúmenes: 1
• Idioma: Inglés