Hsp90 in Cancer: Beyond the Usual Suspects, the latest volume in the Advances in Cancer Research series, focuses on the multifunctional molecular chaperone Hsp90 which regulates the post-translational stability and function of a broad repertoire of client proteins and discusses some of the lesser-known aspects of how Hsp90 and its related family members enable oncogenic transformation and malignant progression. Focuses on the multifunctional molecular chaperone Hsp90 which regulates the post-translational stability and function of a broad repertoire of client proteinsHighlights the rapidly evolving understanding of the fundamental roles of Hsp90 in cancer biology Discusses the lesser-known aspects of how Hsp90 and its related family members enable oncogenic transformation and malignant progression INDICE: 1. Buffering capacity of Hsp90 in cancer Dan Bolon2. Hsp90 interactome Didier Picard3. Functions of the Hsp90 gp96 in cancer Zihai Li4. untitled Paul Workman5. HSP90 in cancer: Transcriptional roles in the nucleus Stuart K. Calderwood6. Chaperone vaccines Michael Graner7. untitled Medhi Mollapour8. Secreted Hsp90 in development and metastasis Lia Patsavoudi9. Hsp90 and regulation of epithelial cell polarity Jennifer Isaacs
- ISBN: 978-0-12-802290-0
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 362
- Fecha Publicación: 01/03/2016
- Nº Volúmenes: 1
- Idioma: Inglés