By integrating the chemical and biological aspects of chemically induced DNA damage, this volume explains genotoxicity at the molecular level, showing the links between a DNA lesion and the resulting cellular or organismic response. Part 1 focuses on selected examples of important DNA lesions and their biological impact. Part 2 covers current advances in assessing and predicting the genotoxic effects of chemicals, taking into account the biological responses mediated by the DNA repair, replication and transcription machineries. It is a modern reference on a key topic in biochemical toxicology that reaches out into molecular biology, molecular medicine and environmental science.
- ISBN: 978-3-527-32295-4
- Editorial: Wiley-VCH
- Encuadernacion: Cartoné
- Páginas: 471
- Fecha Publicación: 23/06/2010
- Nº Volúmenes: 1
- Idioma: Inglés