This unique book highlights key aspects and latest advances of the rapidly developing field of molecular catalysis. It is aimed at a deeper understanding of reaction mechanisms and catalytic cycles at the molecular level and shall provide concepts for catalyst optimization and the rational design of novel, tailor–made catalysts. Researchers working in the field of catalysis as well as graduate students in chemistry will find this book appealing as it covers experimental and theoretical studies (kinetics, model calculations, spectroscopy), along with examples for improved catalysts and their application in organic synthesis, biocatalysis, and supported organometallic catalysis. INDICE: FOREWORD INTRODUCTION 1) MECHANISMS OF ELEMENTARY REACTIONS IN CATALYTIC PROCESSES Introduction 1.1. Quantum Dynamics of Molecular Elementary Processes in Catalytic Transformations 1.2. Activation of Small Molecules with Metal and Metal Oxide Clusters in Inert Gas Matrices 1.3. Single Molecule Spectroscopy of Catalytic Sites and Metal Catalyzed Reaction Steps 1.4. Intermediates and Elementary Reactions in Gold Catalysis 1.5. Diastereoselectivity of Olefin Metathesis 2) NEW CATALYSTS – NEW AND OLD REACTIONS Introduction 2.1. Oxidation Catalysis with the Iron(II)–bispidine/H2O2 system 2.2. Single–site Organochromium Catalysts for High Molecular Weight Polyolefins 2.3. Hydroformylation and Hydrocyanation: Ligand Design for Efficient and Selective Catalysts Based on Theoretical Modelling and Mechanistic Insight 2.4. Strongly Electron Donating Tridente N–Heterocyclic Biscarbene Ligands for Rhodium and Iridium Catalysis 2.5. NHCP Ligands for New Catalysts 3) CATALYSTS IN SYNTHESIS Introduction 3.1. Iridium–Catalysed Allylic Substitutions 3.2. Sequential Catalysis Involving Metal Catalysed Cycloisomerisations and Insertion Cyclisations 3.3. C–N–Coupling Reactions in Catalytic One–Pot Synthesis Using Molecular Group 4 Catalysts 3.4. Sequential Catalysis for the Stereoselective Synthesis of Polyketides 3.5. Modular Assembly of Chiral Catalysts with Polydentate Stereodirecting Ligands 4) STRUCTURES AND MECHANISMS IN BIOLOGICAL CATALYSIS Introduction 4.1. Mechanistic Studies in Enzyme Catalysis 4.2. Conformational Flexibility and Catalytic Reactivity in Phosphoesterases 4.3. Selective Hybrid Catalysts Based on Nucleic Acids 5) STUDIES OF IMMOBILIZED CATALYSTS Introduction 5.1. Dendrimers as Platforms for Stereoselective Catalysis 5.2. Solid Phases as Protective Environments for Biomimetic Catalysts 5.3. High Throughput Screening of Catalysts and Reactions
- ISBN: 978-3-527-33521-3
- Editorial: Wiley VCH
- Encuadernacion: Cartoné
- Páginas: 440
- Fecha Publicación: 14/07/2014
- Nº Volúmenes: 1
- Idioma: Inglés