Sex and Gender Differences in Alzheimers Disease: The Womens Brain Project

Sex and gender differences in Alzheimer's Disease offers for the first time a critical overview of the evidence documenting sex and gender differences in AD neurobiology, biomarkers, clinical presentation, treatment, clinical trials and their outcomes and impact on cargegivers. This knowledge is crucial for clinical development, digital health solution as well as social and psychological support to AD families, in the frame of a precision medicine approach in AD. Comprehensive and critical review of sex differences in Alzheimer's diseaseCombines the knowledge and points-of-view of neuroscientists, medical doctors, psychologists, AI experts, for a 360degree view on the topic and its possible implicationsEdited by the Women's Brain Project, the leading NGO in the field of sex differences in neuroscience INDICE: PART 1 Basic Science 1. Sex differences in animal models 2. Sex differences in pathological mechanisms/estrogen response/cellular and system models 3. Sex differences in microglia and abeta clearance 4. Sex differences in brain vascular biology 5. Sex differences in the cholinergic system PART 2 Clinical science 6. Sex differences in epidemiology 7. Sex differences in neuropsychiatric performance and clinical symptoms 8. Sex differences in CSF biomarkers 9. Sex diff in imaging biomarkers 10. Sex difference in digital biomarkers 11. Sex differences in lifestyle risk factors 12. Sex differences in clinical trials PART 3 Socio-economic aspects 13. Socioeconomic landscape, risk and costs of AD under the sex and gender lens 14. Women living with Alzheimer: a psychosocial perspective 15. Sex differences in caregiving patterns and caregivers needs 16. Communication and ethical themes in AD - the role of gender 17. How to integrate sex and gender in policy making for AD

• ISBN: 978-0-12-819344-0
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 301
• Fecha Publicación: 01/05/2021
• Nº Volúmenes: 1
• Idioma: Inglés