Topical and transdermal drug delivery: principles and practice

INDICE: Preface. Contributors. Part 1. Current science, skin permeation andenhancement approaches. Chapter 1. Skin structure, function and permeation (Heather A. E. Benson). Chapter 2. Passive skin permeation enhancement (Majella E. Lane, Paulo Santos, Adam C. Watkinson, Jonathan Hadgraft). Chapter 3. Electrical and physical methods of skin penetration enhancement (Jeffrey E. Grice, Tarl Prow, Mark Kendall, Michael S. Roberts). Chapter 4. Clinical applicationsof transdermal iontophoresis (D. R. Kalaria, S. Dubey and Y. N. Kalia). Chapter 5. In vitro skin permeation methodology (Barrie Finnin, Kenneth A. Walters and Thomas J. Franz). Chapter 6. Skin permeation assessment: tape stripping (Sandra Wiedersberg and Sara Nicoli). Chapter 7. Skin permeation assessment: microdialysis (R. Holmgaard, JB Nielsen and E. Benfeldt). Chapter 8. Skin permeation assessment: spectroscopic methods (Jon Hadgraft, Majella Lane). Chapter 9.Skin permeation assessment in man: in vitro in vivo correlation (Paul A. Lehman, Sam G. Raney, Thomas J. Franz). Chapter 10. Risk assessment (Jon R. Heylings). Part 2. Topical and Transdermal Product Development. Chapter 11. An Overview of Product Development From Concept To Approval (Adam C. Watkinson). Chapter 12. Regulatory Aspects of Drug Development for Dermal Products (William K. Sietsema). Chapter 13. Toxicological and preclinical considerations for novel excipients and NCEs (Andrew Makin, Jen Thing Mortensen). Chapter 14. Topical product formulation development (Marc B. Brown, Robert Turner and Sian T. Lim).Chapter 15. Transdermal product formulation development (Kenneth J. Miller). Chapter 16. Sensitivity and irritation testing (Belum Viswanath Reddy, Geetanjali Sethi, Howard I. Maibach). Chapter 17. New Product Development for Transdermal Drug Delivery: Understanding the Market Opportunity (Hugh Alsop). Chapter18. Transdermal and topical drug delivery today (Adam C. Watkinson). Chapter 19. Current and future trends: Skin diseases and treatment (Simon G. Danby andMichael J. Cork).

• ISBN: 978-0-470-45029-1
• Editorial: John Wiley & Sons
• Encuadernacion: Cartoné
• Páginas: 440
• Fecha Publicación: 11/11/2011
• Nº Volúmenes: 1
• Idioma: Inglés