The Cerebral Cortex in Neurodegenerative and Neuropsychiatric Disorders: Experimental Approaches to Clinical Issues

The Cerebral Cortex in Neurodegenerative and Neuropsychiatric Disorders: Experimental Approaches to Clinical Issues focuses on how pre-clinical investigations are addressing the clinical issues surrounding the involvement of the cerebral cortex in selected conditions of the nervous system, including Alzheimer's Disease, Parkinson's, addiction, and cardiovascular dysregulation. Each chapter is written by an expert in his/her field who provides a comprehensive review of the clinical manifestations of cortical involvement and experimental techniques currently available to tackle cortical issues in disease. Thus, this present title provides a link between cortical clinical problems and investigational approaches to help foster future research with high translational value. Offers a comprehensive overview on the best available in vivo and in vitro models to study cortical involvementPresents models and specific techniques that help to guide investigators in their choices on how to address research questions experimentallyProvides expert commentary and a perspective on future trends at the end of each chapter Addresses translational advances and promising therapeutic optionsIncludes references to key articles for additional detailed study INDICE: Introductory Chapters 1.  Anatomy of the Cerebral Cortex 2.  Cortical Plasticity in Response to Injury and Disease 3.  Imaging Approaches to Cerebral Cortex Pathology The Cerebral Cortex in Neurodegenerative Disorders 4.  Alzheimer's Disease 5.  Vascular Dementia 6.  Frontotemporal Dementia 7.  Parkinson's Disease and the Cerebral Cortex 8.  Huntington's Disease 9.  Amyotrophic Lateral Sclerosis 10. Cortical Involvement in Multiple Sclerosis    The Cerebral Cortex in Neuropsychiatric Disorders 11. Prefrontal Cortical Abnormalities in Cognitive Deficits of Schizophrenia 12. Role of the Prefrontal Cortex in Addictive Disorders

• ISBN: 978-0-12-801942-9
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 340
• Fecha Publicación: 05/09/2016
• Nº Volúmenes: 1
• Idioma: Inglés