These new volumes of Methods in Enzymology (554 and 555) on Hydrogen Sulfide Signaling continue the legacy established by previous volumes on another gasotransmitter, nitric oxide (Methods in Enzymology volumes 359, 396, 440, and 441), with quality chapters authored by leaders in the field of hydrogen sulfide research. These volumes of Methods in Enzymology were designed as a compendium for hydrogen sulfide detection methods, the pharmacological activity of hydrogen sulfide donors, the redox biochemistry of hydrogen sulfide and its metabolism in mammalian tissues, the mechanisms inherent in hydrogen sulfide cell signaling and transcriptional pathways, and cell signaling in specific systems, such as cardiovascular and nervous system as well as its function in inflammatory responses. Two chapters are also devoted to hydrogen sulfide in plants and a newcomer, molecular hydrogen, its function as a novel antioxidant. Continues the legacy of this premier serial with quality chapters on hydrogen sulfide research authored by leaders in the field Covers conventional and new hydrogen sulfide detection methodsCovers the pharmacological activity of hydrogen sulfide donorsContains chapters on important topics on hydrogen sulfide modulation of cell signaling and transcriptional pathways, and the role of hydrogen sulfide in the cardiovascular and nervous systems and in inflammation INDICE: THE REDOX BIOCHEMISTRY OF HYDROGEN SULFIDE1. Investigating the role of H2S in 4-HNE scavenging Bernhard M.K Gmeiner and Hilde Laggner 2. Inhalation Exposure Model of Hydrogen Sulfide (H2S)-Induced Hypometabolism in the Male Sprague-Dawley Rat Shannon M. BaileyMECHANISMS OF H2S CELL SIGNALING AND TRANSCRIPTIONAL PATHWAYS3. Detection of protein S-sulfhydration by a Tag-Switch technique Ming Xian4. Real-time assays for studying the reactivity of protein thiols with hydrogen sulfide and sulfane sulfur Tobias Dick and Romy Greiner 5. Sulfhydration of H2S protein targets Solomon H. SnyderH2S IN CELL SIGNALING IN THE CARDIOVASCULAR AND NERVOUS SYSTEM AND INFLAMMATORY PROCESSES6. Preconditioning by H2S induces an anti-inflammatory phenotype in ischemia/reperfusion injury Ronald J. Korthuis7. Attenuation of inflammatory responses by H2S in ischemia/reperfusion injury Frank W. Sellke and Neel R. Sodha 8. CD47-dependent regulation of H2S biosynthesis and signaling in T cells David D. Roberts, Anthony L. Schwartz, Thomas Miller and Sukhbir Kaur 9. Regulation of inflammation by H2S John L. Wallace10. H2S and substance P in inflammation Madhav Bhatia11. Role of H2S in synaptic remodeling in brain Neetu TyagiH2S IN PLANTS12. H2S: environmental factor or signalling molecule? John T. Hancock13. Analysis of some enzyme activities of H2S metabolism in plants Zhong-Guang Li14. Sulfide detoxification in mitochondria of Arabidopsis thaliana Rüdiger HellMOLECULAR HYDROGEN15. Molecular hydrogen as a novel antioxidant Shigeo Ohta
- ISBN: 978-0-12-801511-7
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 412
- Fecha Publicación: 15/03/2015
- Nº Volúmenes: 1
- Idioma: Inglés