Prognostic and Therapeutic Applications of RKIP in Cancer

Prognostic and Therapeutic Applications of RKIP in Cancer provides updated reviews on the chemistry, signaling, pre-clinical and clinical activities, and role of RKIP expression levels for diagnostics, prognosis and potential interventions. The development of novel compounds and conjugates that selectively induce RKIP expression in cancer open a novel era of new therapeutics and their potential in the treatment of highly resistant cancers and metastases. Edited and written by internationally renowned experts in the field of novel therapeutics for cancer, this book is a valuable source for cancer researchers, medical scientists, clinicians, clinical pharmacologists, and graduate students. Provides an update from experts in the field on diagnostics, prognostics and therapeuticsBrings a clear overview of recent findings and references, as well as summaries, significant molecular pathways, and conclusions in each chapterProvides a general introductory chapter on contributions in the field and a chapter summary, with synthesized findings and a projection of future goals INDICE: 1. Biochemical, molecular and genetic regulations of RKIP expression 2. Post-translational modifications of RKIP and consequences 3. Molecular signals and cross talks regulated by RKIP 4. Molecular mechanisms that regulate metastasis by RKIP 5. Molecular mechanisms that regulate apoptotic pathways by RKIP 6. In vivo tumor models examining RKIP anti-tumor activities 7. Diagnostic and prognostic roles mediated by RKIP expression levels

• ISBN: 978-0-12-819612-0
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 504
• Fecha Publicación: 02/03/2020
• Nº Volúmenes: 1
• Idioma: Inglés