Quantitative Biomedical Optics: Theory, Methods, and Applications

This is the textbook and reference resource that instructors, students, and researchers in biomedical optics have been waiting for. Comprehensive and up to date, it covers a broad range of areas in biomedical optics, from light interactions at the single-photon and single-biomolecule levels, to the diffusion regime of light propagation in tissue. Subjects covered include spectroscopic techniques (fluorescence, Raman, infrared, near-infrared, and elastic scattering), imaging techniques (diffuse optical tomography, photoacoustic imaging, several forms of modern microscopy, and optical coherence tomography), and laser-tissue interactions, including optical tweezers. Topics are developed from the fundamental principles of physical science, with intuitive explanations, while rigorous mathematical formalisms of theoretical treatments are also provided. For each technique, descriptions of relevant instrumentation and examples of biomedical applications are outlined, and each chapter benefits from references and suggested resources for further reading, and exercise problems with answers to selected problems. INDICE: 1. Nomenclature; 2. Overview of tissue optical properties; 3. Introduction to biomedical statistics for diagnostic applications; 4. General concepts of tissue spectroscopy and instrumentation; 5. Autofluorescence spectroscopy and reporter fluorescence; 6. Raman and infrared spectroscopy of vibrational modes; 7. Elastic and quasi-elastic scattering from cells and small structures; 8. Diffuse reflectance spectroscopy at small source-detector separations; 9. Transport theory and the diffusion equation; 10. Continuous-wave methods for tissue spectroscopy; 11. Time-domain methods for tissue spectroscopy in the diffusion regime; 12. Frequency-domain methods for tissue spectroscopy in the diffusion regime; 13. Instrumentation and experimental methods for diffuse tissue spectroscopy; 14. Diffuse optical imaging and tomography; 15. In vivo applications of diffuse optical spectroscopy and imaging; 16. Combining light and ultrasound: acousto-optics and opto-acoustics; 17. Modern optical microscopy for biomedical applications; 18. Optical coherence tomography; 19. Optical tweezers and laser-tissue interactions.

• ISBN: 978-0-521-87656-8
• Editorial: Cambridge University Press
• Encuadernacion: Cartoné
• Páginas: 698
• Fecha Publicación: 07/01/2016
• Nº Volúmenes: 1
• Idioma: Inglés