Implementing Precision Medicine in Best Practices of Chronic Airway Diseases

Implementing Precision Medicine in Best Practices of Chronic Airway Diseases provides a comprehensive overview of the application of precision medicine in airway diseases. With precision Medicine increasingly recognized as the way forward in optimal patient care, it is now considered in the area of chronic airway diseases to achieve optimal control of disease, higher patient satisfaction, and disease prevention. As medical research continues to fund this area, it highlights the need for implementation of the principles of precision medicine into the management of chronic airway diseases. It is clear that chronic airway diseases are heterogeneous and that a personalized approach is warranted by which the treatment is tailored to the level of the individual patient. Written for basic researchers in this area and medical doctors Implementing Precision Medicine in Best Practices of Chronic Airway Diseases provides guidance on the implementation of the principles of precision medicine into further research as well as daily clinical practice. Bridges the gap between precision medicine research and the implementation of the principles into and daily clinical practiceIncludes contributions from key opinion leaders in the field of airway disease for a worldwide perspectiveDiscusses precision medicine in terms of personalized medicine, prediction of success, participation of the patient, and prevention of disease INDICE: I. The concept of Precision Medicine and Precision Health 1. The audacious goal of precision medicine 2. The tools of Precision Medicine 3. The stakeholders network II. Shortcomings of current care pathways for chronic airways diseases 4. The global burden of chronic airways diseases 5. Unmet needs in chronic respiratory diseases III. Personalized care: endotype-driven treatment 6. New approaches defining allergic diseases endotypes 7. Factors modulating the disease endotype 8. Linking disease phenotypes and endotypes 9. Validation and qualification of biomarkers and their translation into pathway-specific diagnostic tests 10. Endotype-driven approach for rhinitis 11. Endotype-driven approach for rhinosinusitis 12. Endotype-driven approach for asthma 13. Endotype-driven approach for COPD 14. Big data translation into clinical decision algorithms 15. Predictive aspects - measures of success 16. Critical issues for the endotype/biomarkers driven approach 17. Key points for moving the endotypes field forward IV. Health information technology and PM 18. Innovative health IT 19. Correlation and trend analysis tools ~ 20. Real-time clinical decision support at the point of care 21. Patient-friendly HIT tools and the advent of crowdsourcing clinical trials 22. Global HIT systems - opportunities and challenges V. The vision of precision health 23. Identification of 'classical' and 'novel' phenotypes in existing birth cohorts, their validation and redefinition 24. Discovery of the relevant mechanisms 25. The merger between traditional medicine and population health 26. Critical entry points - genetics and epigenetics 27. Critical entry points - microbiome VI. Participation of the patient 28. The patient-centered environment 29. Interpersonal dimensions (relationship) 30. Clinical dimensions (provision of care) 31. Structural dimensions (system's features) 32. The KPIs of patient centered environment VII. Bringing Precision Medicine to the clinic 33. Improved understanding and common usage of disease phenotypes, endotypes, biomarkers and precision therapies at the point of care 34. Revised disease nomenclature including disease endotypes 35. Full patient monitoring using novel digital technology and the concept of endotypes/novel biomarkers/patient centered care 36. Global, multi-discipline partnerships 37. Rethinking healthcare 38. The right balance between research and political priorities 39. Stakeholders network coordination

• ISBN: 978-0-12-813471-9
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 224
• Fecha Publicación: 01/08/2018
• Nº Volúmenes: 1
• Idioma: Inglés